After being delayed for nearly a month and moved from Sao Paolo Brazil to the brand new UFC Apex in Las Vegas, UFC 250 will take place on Saturday night. The best pound-for-pound fighter in women’s mixed martial arts will take center stage as Amanda Nunes puts her UFC Featherweight Championship on the line against Felicia Spencer. And with millions on the line in UFC DFS tournaments, cash games and 50-50s on FanDuel and DraftKings, UFC daily Fantasy players will be looking for value in the UFC DFS fighter pool for Saturday.

The 12-fight UFC 250 card features undefeated prospects like bantamweight Sean O’Malley, light heavyweight Sean Menifield and featherweight Chase Hooper. But with all three facing some of their stiffest challenges to date, can any of them be trusted in your UFC DFS lineups on Saturday? Before locking in any UFC 250 DFS picks, be sure to check out the optimal UFC DFS strategy and advice from SportsLine’s Mike McClure.

McClure is a predictive data engineer and DFS pro with almost $2 million in career winnings. He’s crushed his DFS selections recently, producing tournament rosters that have cashed huge in multiple sports over the past few years.

At UFC Fight Night: Woodley vs. Burns, McClure was all over Mackenzie Dern and Jamahal Hill as two of his top picks. The results: both fighters scored first-round stoppages, and anybody who followed McClure’s advice was poised for a profitable day. 

Now, McClure has set his sights on UFC 250 and locked in his top MMA daily Fantasy picks. You can only see them here.

Top UFC 250 DFS predictions

For UFC 250, McClure is high on Amanda Nunes ($9,400 on DraftKings, $23 on FanDuel) as she takes on Felicia Spencer for the UFC Women’s Featherweight Championship. The “Lioness” is riding a 10-fight winning streak into UFC 250 and she’s the only woman in the history of the sport to simultaneously hold championships in two weight classes.

Nunes is the more well-rounded fighter by almost any metric, but with Spencer having an outside chance of scoring a submission if the fight goes to the ground, it’s likely that Nunes will look to keep the fight standing where she has her most considerable advantage. Nunes has an impressive work rate on her feet, landing 4.62 significant strikes per minute while absorbing just 3.18 significant strikes per minute.

Part of McClure’s optimal UFC 250 DFS strategy also includes rostering Herbert Burns ($8,900 on DraftKings, $18 on FanDuel), who is 10-2 and takes on Evan Dunham in a catchweight bout at 150 pounds. The brother of last week’s main event winner Gilbert Burns, Herbert Burns is coming off a dynamic performance in his UFC debut against Nate Landwehr at UFC Fight Night 166.

Burns scored a first-round knockout via a vicious knee and has now recorded three consecutive first-round knockouts. Meanwhile, the 38-year-old Dunham hasn’t won since September 2016 and he’s been knocked out via knees in each of his last two fights. Look for Burns to score an early decision and rack up the points for UFC daily Fantasy players on Saturday night.

How to make UFC DFS picks

McClure is also targeting a value fighter who is a must-roster because his fight is a huge mismatch. This pick could be the difference between cashing huge in MMA DFS or going home with nothing. You can see all of McClure’s MMA DFS picks and advice here.

So what are the optimal DraftKings and FanDuel picks for UFC 250? And which value fighter needs to be in your lineup? Visit SportsLine now to see DFS millionaire Mike McClure’s complete optimal picks for Saturday’s UFC 250, and cash in big on MMA DFS.